بررسی ویژگی‌های جمعیت‌شناختی و شاخص‌های عملکرد کلیوی بیماران با مسمومیت حاد ترامادول در بیمارستان آیت‌ا... طالقانی ارومیه

 Background & Aims: Since acute tramadol poisoning is related to several clinical complications. The aim of this study was to evaluate the epidemiologic, demographic and renal function indices in acute tramadol intoxicated patients.Materials & Methods: In this retrospective descriptive study, all patients admitted to Taleghani hospital of Urmia, Iran, were evaluated during a one-year period. Patients’ demographic data and the results of laboratory tests were imported to computer and analyzed.Results: From 254 tramadol intoxicated patients, 219 (86.2%) were male and 35 (13.8%) female. The patients’ mean age was 23.29 (SD = 7.04) years. Most patients were single (69.3%). The ingested tramadol doses were known in 162 cases with average of 1837.35 mg (SD = 2347.36). Three patients (1.2%) had hyperkalemia, Based on laboratory and clinical findings, renal dysfunction and acute renal failure were detected in 29 and 6 patients, respectively. Four patients with acute renal failure recovered by treatment, one patient underwent hemodialysis and one patient expired despite of medical cares.Conclusion: Acute renal failure and hyperkalemia are side effects of tramadol intoxication that should be considered in diagnosis, treatment and follow-up of these patients. Our study may be a beginning for further investigations for renal complications of tramadol toxicity. SOURCE: URMIA MED J 2015: 25(12): 1066 ISSN: 1027-3727